Clinical Neurology and Neuroscience

Volume 2, Issue 1, March 2018

  • SUN13837 in Treatment of Acute Spinal Cord Injury, the ASCENT-ASCI Study

    Benjamin Levinson, James Lee, Hubert Chou, Dennis Maiman

    Issue: Volume 2, Issue 1, March 2018
    Pages: 1-8
    Received: 26 October 2017
    Accepted: 8 November 2017
    Published: 23 December 2017
    Abstract: The purpose of this study was to assess the safety and efficacy of SUN13837, a bFGF mimetic, for the treatment of acute cervical spinal cord injury. In a 26-week, double-blind trial, 65 subjects were randomized (1:1) by stratum within 12 hours of injury to 1 mg/kg/day of intravenous SUN13837 (SUN) or matching placebo (pbo) for no less than 7 and no... Show More
  • Skin Picking in Individuals with Intellectual DisabilitySkin Picking in Individuals with Intellectual Disability

    Allison Cowan, Jason Lee

    Issue: Volume 2, Issue 1, March 2018
    Pages: 9-11
    Received: 5 August 2017
    Accepted: 20 November 2017
    Published: 9 January 2018
    Abstract: Individuals with Intellectual Disability seek treatment from primary care physicians, neurologists, and psychiatrists for excoriation disorder, a disorder described as the picking of ones’ skin resulting in sores. There is a significant financial and emotional cost to people with this disorder. There is a lack of research in the area of co-occurrin... Show More
  • Neuroprotective and Therapeutic Role of Omega-3 Against Oxidative Stress and Neurotransmitter Disturbances in Rotenone-Induced Mice Model of Parkinson's Disease

    Nagi Ali Ibrahim, Yasser Ashry Khadrawy, Soliman Sayed Ibrahim, Noura El-Sayed Ezzat

    Issue: Volume 2, Issue 1, March 2018
    Pages: 12-22
    Received: 16 November 2017
    Accepted: 5 December 2017
    Published: 7 February 2018
    Abstract: The present study aimed at evaluating the protective and therapeutic efficacy of omega-3 against motor impairment and brain biochemical disturbances in rotenone-induced mice model of Parkinson's disease (PD). Sixty animals were divided into six groups (10 each): mice of the 1st group were used as controls, they were injected subcutaneously ( s c ) ... Show More