System Organization of Clinical Symptoms and EEG-Characteristics of Patients with Depressive Disorders in Harmonic Sound Therapy
Elena Grigorieva,
Alexey Dyakonov,
Valeriy Volovenko
Issue:
Volume 2, Issue 3, September 2018
Pages:
46-55
Received:
25 September 2018
Accepted:
22 December 2018
Published:
29 January 2019
Abstract: The work is devoted to the search for the systemic organization of clinical symptoms and EEG characteristics of patients with recurrent depressive disorders. It determines the effect of harmonic sound in accordance with the extremes of the maximum and/or minimum EEG spectrum on clinical and EEG characteristics of patients, loosening of stable pathological relationships in order to reduce or eliminate depression. The study involved 58 patients. 35 of them were diagnosed with prolonged and chronic depressive disorder, which to no avail was treated with various antidepressants of the group of SSRIs in combination with benzodiazepines or small doses of atypical (olanzapine, sulpiride) or classical (chlorprotixen, sonapax) antipsychotics. At the time of sound therapy, the drugs were not canceled. 22 patients had repeated depressive episode in the past (two to four weeks ago), untreated. The search for the systemic organization of clinical symptoms and EEG characteristics was carried out using analytical mathematics. In this section factor analysis with factor rotation were used. The positive outcome of the sessions of sound exposure, as well as the reaction to the sound of the last session (no drowsiness or vigor, there is a weakening or elimination of depression), and the number of sessions depended on the removal of the most stable combinations of symptoms (according to the HAM- D scale). They reflected the reciprocity of their own symptoms of depression and anxiety in both groups of patients and made a "hard link" of the system. Other combinations of symptoms-flexible links of the system-are less stable. Acting on them in a stable pathological condition (depression) are less radical. Harmonic sound effects cause a significant restructuring of the background EEG observed at the time of exposure and after it in both groups of patients. The features of EEG in patients in complete or incomplete remission, as well as in the absence of the effect of treatment. Neurophysiological "hard link" of the system organization of EEG characteristics could not be identified. An attempt to explain the results is made. Perhaps the "hard link" of the system organization of EEG characteristics is at a different energy level or requires a different mathematical approach.
Abstract: The work is devoted to the search for the systemic organization of clinical symptoms and EEG characteristics of patients with recurrent depressive disorders. It determines the effect of harmonic sound in accordance with the extremes of the maximum and/or minimum EEG spectrum on clinical and EEG characteristics of patients, loosening of stable patho...
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Spinal Epidermoids - Rare Tumours Posing a Diagnostic Dilemma
Sanjay Kumar,
Krishan Kumar Yadav,
Saurabh Kumar Verma
Issue:
Volume 2, Issue 3, September 2018
Pages:
56-60
Received:
18 December 2018
Accepted:
3 January 2019
Published:
29 January 2019
Abstract: Spinal epidermoids are rare tumors comprising less than 1% of all intraspinal tumors. These tumors are usually found as intramedullary space occupying lesions (SOLs) in cervico-dorsal and as intradural SOLs in lumbo-sacral region. Thier origin has been advocated to be congenital or acquired. These tumors have been reported in patients of age group 03 yrs to 55 yrs in various case reports/small series in literature. The usual presentation is that of slowly progressive spastic paraparesis / quadriparesis with or without sphincter involvement as in IMSOLs / IDEMs lesions of the spinal cord. These tumors pose a diagnostic dillema due to there rarity. The diagnosis of these tumors may be delayed as they have similar symptoms and signs as in any other intradural spinal patholgy. The preoperative diagnosis can be made with reasonable certainity dedicated MRI sequences (diffusion weighted & ADC) are carried out. Since these tumors are benign, an early diagnosis gives the patient a realtively good prognosis. We report two such unusual cases which came as diagnostic surprise on operative table and that too within a period of 06 months. Microscopic total excision relatively early in the course of the illness in both these patients had satisfactory outcome with good neurological recovery and no recurrence over last 24 months.
Abstract: Spinal epidermoids are rare tumors comprising less than 1% of all intraspinal tumors. These tumors are usually found as intramedullary space occupying lesions (SOLs) in cervico-dorsal and as intradural SOLs in lumbo-sacral region. Thier origin has been advocated to be congenital or acquired. These tumors have been reported in patients of age group ...
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