Volume 4, Issue 4, December 2020, Page: 92-97
The Nutritional Profile Among Children with Epilepsy at Sanglah Hospital
Johanes Ari Cahyo Prabowo, Department of Child Health, Faculty of Medicine Udayana, Sanglah Hospital Bali, Bali, Indonesia
I Gusti Ngurah Made Suwarba, Department of Child Health, Faculty of Medicine Udayana, Sanglah Hospital Bali, Bali, Indonesia
Dewi Sutriani Mahalini, Department of Child Health, Faculty of Medicine Udayana, Sanglah Hospital Bali, Bali, Indonesia
Received: Nov. 30, 2020;       Accepted: Dec. 9, 2020;       Published: Dec. 16, 2020
DOI: 10.11648/j.cnn.20200404.15      View  82      Downloads  49
One million people live with epilepsy in Indonesia. The using of antiepileptic drug for the long time can affect the nutritional and growth profile among children with epilepsy. The purpose of this study is to determine the characteristics of nutritional profile among children with epilepsy at Sanglah Hospital Denpasar. This study is an observational retrospective study using a descriptive design that examined the nutritional profile among hospitalized children with epilepsy at the pediatric neurology ward at Sanglah Hospital, Denpasar. This study was done retrospectively based on secondary data since January 1, 2017 until December 31, 2019, with 95 samples population were collected. The mean age of sample population was 5,4 years (SD±4.3) with majority samples were male 60 children (63.1%) and female were 35 children (36,9%). The majority of samples had general epilepsy 59 children (62.1%), followed by focal epilepsy 23 children (24.2%) and general combined focal epilepsy 13 children (13.7%). In this study, the most common etiology of epilepsy were idiopathic 53 children (55.8%), followed by structural 30 children (31.6%), infection 8 children (8.4%), immunology and metabolic 4 children (4.2%). The most of sample population had normal nutritional status based on waterlow method (weight for height) was 55,4% and height for age was 74,7%. However, there were increasing number of overweight/obesity was 14 children (14,7%) with history of prolonged anti epileptic drug more than 12 month that using phenobarbital, phenytoin, and valproic acid for medication. The short stature was noted among 24 children (25,3%) of samples, with history of phenobarbital, phenytoin and carbamazepine medication. Sample population with moderate of protein energy malnutrition was 8 children (8.4%) with dysfunction of oromotor. We conclude that almost children with epilepsy at Sanglah hospital had normal nutritional status and height stature. However regular follow up of antropometric status and diagnostic serum calcium, and folic acid should be done for early detection of overweight and obesity along with short stature.
Nutritional Profile, Epilepsy, Antiepileptic Drugs (AED)
To cite this article
Johanes Ari Cahyo Prabowo, I Gusti Ngurah Made Suwarba, Dewi Sutriani Mahalini, The Nutritional Profile Among Children with Epilepsy at Sanglah Hospital, Clinical Neurology and Neuroscience. Vol. 4, No. 4, 2020, pp. 92-97. doi: 10.11648/j.cnn.20200404.15
Copyright © 2020 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Brodie MJ, Schachter SC, Kwan P. Epidemiology and prognosis. Fast Fact: Epilepsy Revised 5th edition. Oxford: Health Press Limited. 2012; 9-11.
Irawan M, Setyo H, Nelly A, et al. Epilepsi pada anak. Badan Penerbit Ikatan Dokter Anak Indonesia. 2016.
Wieser HG dan Silfvenius H. Overview: Epilepsy surgery in developing countries. Epilepsia. 2000; 28-0.
PERDOSSI. Kelompok Studi Epilepsi Perhimpunan Dokter Spesialis Saraf Indonesia. Pedoman tatalaksana epilepsi. Jakarta. 2011.
Robert S F, Helen C, Norimichi H, Jacquelline F. Operational classification of seizures type by the International League Against Epilepsy: Position paper of the ILAE commission for classification and terminology. Epilepsia, 2017; 58 (4): 522-530.
Damayanti R, Sri Sudaryati N, Yoga D, Conny F. Asuhan nutrisi pediatri. UKK Nutrisi dan Penyakit Metabolik. BP IDAI. 2011: 3.
Aydin, Kartal. High rates of malnutrition and epilepsy: two common comorbidities in children with cerebral palsy. Turkish Journal of Medical Sciences. 2019; 49: 33-37.
Teng Y, Cheng H, Hung Y. Long term antiepileptic drug therapy contributes to the acceleration of atherosclerosis. Epilepsia. 2009; 50 (6): 1579-1586.
Guo CY, Ronen GM, Atkinson SA. Long-term valproate and lamotrigine treatment may be a marker for reduced growth and bone mass in children with epilepsy. Epilepsia 2001; 42: 1141–1147.
Robert S, Helen C, Carol D, Jacquelline A, Sheryl R, Norimichi H, et al. Instruction manual fot the ILAE 2017 operational classification of seizure types. Epilepsia 2017; 58 (4): 531-542.
Jose R, Hardjoedi A, Aditiawati, Aman B, Nanis A, Eka A, et al. Perawakan pendek pada anak dan remaja di Indonesia. BP IDAI. 2017; 1-2.
Hokken-Koelega ACS. Diagnostic workup of the short child. Horm Res. 2011; 76 (Suppl 3): 6-9.
Fernandez R, Correa C, Bianchin M, Perry I. Anthropometric profile and nutritional intake in patients with epilepsy. Nutr Hosp. 2015; 32 (2): 817-22.
IGN Made Suwarba. Insidens dan karakteristik klinis epilepsi pada anak. Sari Pediatri 2011; (13): 2.
Elliot JO, Lu B, Shneker B, Moore J. Comorbidity, health screening, and quality of life among persons with a history of epilepsy. Epilepsy and Behaviour. 2009; 14 (1): 125-129.
Tobias L, Dahl J, Lennart M, Bryan K. Evaluation of acceptance and commitment therapy for drug refractory Epilepsy: A Randomized Controlled Trial in South Africa A Pilot Study. Epilepsia, 2006; 47 (12): 2173–2179.
Verroti A, Pascarella R, Trotta D, Giuva T. Hyperhomocysteinemia in children treated with sodium valproate and carbamazepine. Epilepsy Res. 2000; 41: 253-257.
Victor Biton. Effect of antiepileptic drugs on bodyweight. CNS Drugs. 2012; 17 (11): 781-91.
Gaspari C, Guerreiro C. Modification in body weight associated with antiepileptic drugs. Neuro-Psiquiatr. 2010; 68: 2.
Valmadrid C, Voorhees C, Litt B, Schneyer CR: Practice patterns of neurologists regarding bone and mineral effects of antiepileptic drug therapy. Arch Neurol 2001, 58: 1369–1374.
Browse journals by subject